Now this is something I'm into. We did a Western campaign with vampires, mythological creatures, magic, and all that a couple years ago. What system are you using? We used Edge of the Frontier, an Edge of the Empire reskin, for ours. Then we homebrewed the setting.
Also, have you read Issac's Storm? It is a non-fiction account of the Galveston Hurricane as framed around the U.S. Weather Bureau chief in town and his brother. It also dives into the history of the U.S. Weather Bureau and their relationship with other countries and organizations. Absolutely amazing read.
Have you read Isaac’s Storm by Peter Larson*? It’s about the 1900 Hurricane and is written by the same guy who wrote The Devil in the White City that’s being made into a movie. It’s a fantastic read and really gave me perspective on the region after moving to Houston years back. I highly recommend it if you haven’t already.
edit- fixed speeling